International Immunocompromised
Host Society 22nd Symposium

Annual Congress Swiss Society for
Allergology and Immunology

«Infection and immunity – Are you competent?»

Program

Preliminary Program THURSDAY

16:00 – 16:30
General

Welcome to Basel - welcome to the joint meeting of ICHS and SSAI

Hans H. Hirsch, Basel (CH) / Mike Recher, Basel (CH)
16:30 – 18:00
Joint Session

Plenary Session 1: Infection and immunity – Are you competent?

Hans H. Hirsch, Basel (CH) / Mike Recher, Basel (CH)

Allergic diseases as inborn errors of immunity

Josh Milner, New York (US)

How the immune response modifies antimicrobial therapy decisions

Annelies Zinkernagel, Zurich (CH)

Infection and Immunity: The Challenge of Safe Xenotransplantation

Jay Fishman, Boston (US)
18:00 – 18:45
Joint Session

Evening Reception

18:45 – 20:15
SSAI Session

SSAI Council Dinner

18:45 – 20:15
ICHS Session

ICHS GENERAL ASSEMBLY

20:15 – 22:15
ICHS Session

ICHS COUNCIL DINNER

Preliminary Program FRIDAY

07:00 – 08:00
General

Registration and Room Finding

08:00 – 08:50
ICHS Session

MEET THE EXPERT 1

Clinical and diagnostic considerations in immunocompetent vs immunodeficient patients (case-based)

When Imaging goes viral…Focus on Corona, CARVs and CMV

Jens Bremerich, Basel (CH)

Clinical, diagnostic and functional integration: The lung expert‘s view

Daiana Stolz, Basel (CH)
08:00 – 08:50
ICHS Session

MEET THE EXPERT 2

Epidemiology and management of infections with new therapies in heme-onc and HCT (case-based)

The new –nib on the block

Georg Maschmeyer, Berlin (DE)

The new block on the -mab

Johan Maertens, Leuven (BE)
08:00 – 08:50
SSAI Session

MEET THE EXPERT 3: Meet the Allergologist

Immediate type allergy

Food Allergy, what‘s new?

Barbara Ballmer, St.Gallen (CH)

Understanding antibiotic allergy

Kathrin Scherer Hofmaier, Aarau (CH)
08:00 – 08:50
SSAI Session

MEET THE EXPERT 4: Meet the translational immunologist

Targeted treatment of the immun-dysregulated patient based on molecular mechanisms

... in the immunodeficient patient

Mike Recher, Basel (CH)

... in immune-oncology

Heinz Läubli, Basel (CH)
08:50 – 09:00
General

Time for Room Change

09:00 – 10:00
Joint Session

Plenary Session 2: When too little immunity turns bad… Session dedicated to Dr. Robert Finberg

Roy Chemaly, Houston (US) / Mario Fernández-Ruiz, Madrid (ES)

When immunodeficiency looks like infection...

Steven Holland, Bethesda (US)

When infection looks like immunodeficiency

Jay Fishman, Boston (US)
10:00 – 10:30
General

COFFEE BREAK / POSTER WALK (Posters / Industry Expo)

10:30 – 11:50
ICHS Session

Parallel Session 1: Invasive Fungal Infections

Risk, and drugs and personalized medicine

Murat Akova, Ankara (TR) / Tobias Hohl, New York (US)

When things get “IFI” – clinical clues in heme-onc, HCT, and SOT

Nina Khanna, Basel (CH)

Is pre-emptive anti-fungal therapy ready for prime time ?

Johan Maertens, Leuven (BE)

Genetic risk stratifiers: Pentraxin paradigm and what’s in the pipeline

Pierre-Yves Bochud, Lausanne (CH)

New drugs, new goals, new guidelines

Monica Slavin, Melbourne (AU)
10:30 – 11:50
ICHS Session

Parallel Session 2: Big Data

AI for Diagnosis, Risk factors and Treatment Outcomes

Andri Rauch, Berne (CH) / Karoline Leuzinger, Basel (CH)

The Swiss Cohort Studies: Track record and way forward

Nicolas Müller, Zurich (CH)

The Swiss Personalized Health initiative

Adrian Egli, Basel (CH)

Platform to evaluate outcomes for immunodysfunctional patients: PERSIMUNE

Jens Lundgren, Copenhagen (DK)

Transforming healthcare with the iBox prediction system

Marc Raynaud, Paris (FR)
10:30 – 11:50
SSAI Session

Parallel Session 3: Myeloid cell dysregulation

Mastocytosis: Clinical manifestations and novel treatment strategie

Karin Hartmann, Basel (CH)

Eosinophilic airway diseases: basic science, clinical manifestations and future challenges

Celeste Porsbjerg, Copenhagen (DK)

Histicytic disorders

Julien Haroche, Paris (FR)

Targeting "Don't eat me" signals to treat hematologic malignancies

Alexandre Theocharides, Zurich (CH)
10:30 – 11:50
SSAI Session

Parallel Session 4: Infections in primary immunodeficiency

Thomas Hauser, Zurich (CH)

Overview of primary immunodeficiencies – basics

Isabelle Meyts, Leuven (BE)

Primary immunodeficiency – Infectious clues and diagnosis

Nizar Mahlaoui, Paris (FR)

Clinical approach to the pediatric patient – etiological and antimcicrobial treatment

Thomas Lehrnbecher, Frankfurt (DE)

Clinical approach to the adult patient – etiological and antimcicrobial treatment

Peter Jandus, Geneva (CH)
11:50 – 12:00
General

Time for Room Change

12:00 – 13:20
Industry Symposia

Industry Lunch Symposium - CSL Behring AG

Adrian Zürcher, (CH)

Burdon of infection in SID

Peter Jandus, Geneva (CH)

SIDs in hemato-oncological situations

Sacha Zeerlder, Lucerne (CH)

Where will we see SIDs in the future?

Kirsten Wittke, Berlin (DE)
12:00 – 13:20
General

Lunch Break - Posters / Poster Walk/Industry Expo

12:00 – 13:20
Industry Symposia

Industry Lunch Symposium - Takeda International

Robin Avery, Baltimore (US) / Hans H. Hirsch, Basel (CH)

Dancing with the Troll – The lab perspective

Karoline Leuzinger, Basel (CH)

Precise and Personalized is Best Against the CMV Troll - The SOT Perspective

Camille N. Kotton, Boston (US)

Taming the CytomegaloBeast: Tools in our Armamentarium – The HCT perspective

Roy Chemaly, Houston (US)
13:20 – 13:30
General

Time for Room Change

13:30 – 15:00
ICHS Session

Parallel Session 5: The BEST OF ICHS

CORONA COMPETENCE

Nicolas Müller, Zurich (CH) / Malgorzata Mikulska, Genoa (IT)

Virology

Roy Chemaly, Houston (US)

Solid organ

Robin Avery, Baltimore (US)

HCT

Monica Slavin, Melbourne (AU)

Autoimmunity

Jose-Maria Aguado, Madrid (ES)
13:30 – 15:00
ICHS Session

Parallel Session 6: Immunity is down - just jack it up

Thomas Lehrnbecher, Frankfurt (DE) / Camille N. Kotton, Boston (US)

Treating infections with check-point inhibitors?

Irene Cortese, Bethesda (US)

T-cell guided antiviral therapy – ready for use?

Oriol Manuel, Lausanne (CH)

Transfer of antigen-specific immune effectors – Just do it!

Patrizia Comoli, Pavia (IT)

Energy management in viral infection

Andreas Bergthaler, Vienna (AT)
13:30 – 15:00
SSAI Session

Parallel Session 7: Laboratory Diagnostics

Ingmar Heijnen, Basel (CH) / Luca Bernasconi, Aarau (CH)

Donor-specific Antibodies: Why measure it and what we do about it

Stefan Schaub, Basel (CH)

A novel functional mast cell assay for the detection of allergies

Alexander Eggel, Berne (CH)

Clinical application of genetic testing in primary immunodeficiencies

Johannes Trück, Zurich (CH)

Anti-cytokine autoantibodies: When and how to measure?

Rainer Doffinger, Cambridge (GB)
13:30 – 15:00
SSAI Session

Parallel Session 8: Experimental Immunology

Daniela Latorre, Zurich (CH) / Daniel Legler, Kreuzlingen (CH)

Systems Serology

Galit Alter, Boston (US)

CD4 T cells Sans Frontières: division of labor in the lung

Carolyn King, Basel / Lausanne (CH)

Coronin 1, T cell homeostasis and immunity: Getting it just right

Jean Pieters, Basel (CH)

Specialized eosinophils mediate host defense and immune regulation during intestinal inflammation

Isabelle Arnold, Zurich (CH)
15:00 – 15:30
General

COFFEE BREAK

15:30 – 17:00
Joint Session

Plenary Session 3: When too much immunity turns bad… (Aberrant responses to microbes, drugs, and vaccines)

Mike Recher, Basel (CH) / Carol Kaufman, (CH)

Genetic Susceptibility to Epstein Barr virus infection

Alain Fischer, Paris (FR)

The human genetic and immunological determinants of life-threatening COVID-19

Jean-Laurent Casanova, New York (US)
17:00 – 17:15
General

Time for Room Change

17:15 – 18:45
Industry Symposia

Industry Afternoon Symposium - Mundipharma

Current and future directions for the management of invasive fungal infections in immunocompromised patients

Samir Agrawa, (GB)

Welcome and introduction

Samir Agrawa, (GB)

Importance of PK/PD: optimising antifungal drug dosing

Russell Lewis, (IT)

Key challenges in the clinical management of invasive candidiasis: the value of a patient-tailored approach

Jose-Maria Aguado, Madrid (ES)

Addressing unmet needs of the current treatment paradigm: novel antifungals in development

Thierry Calandra, Lausanne (CH)

Questions and answers

17:15 – 18:45
Industry Symposia

Industry Afternoon Symposium - TBD

17:15 – 18:45
General

Posters / Poster Walk / Industry Expo    

Preliminary Program SATURDAY

07:00 – 08:00
General

Registration and Room Finding

08:00 – 08:50
ICHS Session

MEET THE EXPERT 5

Microbe alarm before transplantation – You’re on call… (Case-based - When to treat, when to defer, when to reject…)

...the SOT perspective

Paolo Grossi, Varese (IT)

...the HCT perspective…

Zenia Papanicolaou, New York (US)
08:00 – 08:50
ICHS Session

MEET THE EXPERT 6

How immunocompromised is your patient ? (case-based)

Which clinical criteria inform my daily practice ?

Monica Slavin, Melbourne (AU)

Which specific or adjunctive tests can help to inform diagnosis and management?

Mario Fernández-Ruiz, Madrid (ES)
08:00 – 08:50
SSAI Session

MEET THE EXPERT 7: Meet the Aerobiologists

Infection and respiratory allergy

Pollen exposure in allergic as well as non allergic subjects increases the susceptibility to respiratory viral infection, including to SARS-CoV-2

Stefanie Gilles, Munich (DE)

Respiratory viral infection increases the risk of developing respiratory allergies

Marie-Charlotte Brüggen, Zurich (CH)
08:00 – 08:50
SSAI Session

MEET THE EXPERT 8: Meet the Swiss Young Immunologists (SYIS)

Next generation immunologists

Best SYIS abstract 1+2

Daniela Latorre, Zurich (CH)

Best SYIS abstract 3+4

Sinduya Krishnarajah, Zurich (CH)
08:50 – 09:00
General

Time for Room Change

09:00 – 10:00
Joint Session

Plenary Session 4: Corona and CoVID19 2022: State-of the-Art in the third pandemic year after start - (Session dedicated to Dr. Francisco Marty)

Monica Slavin, Melbourne (AU) / Hans H. Hirsch, Basel (CH)

SARS-CoV-2 and CoVID19 – Clinical trials, real-time translation and way forward

Lindsey R. Baden, Boston (US)

The origin and ongoing evolution of SARS-CoV-2

Eddie Holmes, Sydney (AU)
10:00 – 10:30
General

COFFEE BREAK / POSTER WALK (Posters / Industry Expo)

10:30 – 11:50
ICHS Session

Parallel Session 9: Bacterial Infections, Immune dysfunction and critical illness

Nina Khanna, Basel (CH) / Mario Fernández-Ruiz, Madrid (ES)

Sepsis State-of-the-Art and what is unique to the immunocompromised host?

Thierry Calandra, Lausanne (CH)

Breaches in defence: cathethers, ports and implants post-transplant

Paolo Grossi, Varese (IT)

MDR-bugs in heme-onc and HCT: Selection, scare and stewardshi

Murat Akova, Ankara (TR)

MDR-bugs in solid organ transplantation: Who is at risk and why?

Jose-Maria Aguado, Madrid (ES)
10:30 – 11:50
ICHS Session

Parallel Session 10: Community-acquired respiratory viruses in Immunocompromized Hosts

Maddalena Peghin, Varese (IT) / Laurent Kaiser, Geneva (CH)

CARV pathogenesis – clues from the good, the bad, and the ugly

Chrysanthi Skevaki, Giessen (DE)

How do I manage CARVs in heme-onc and HCT?

Marie von Lilienfeld-Toal, Jena (DE)

Perspective: Infection control, and then what: antivirals, vaccines or immunotherapy ?

Roy Chemaly, Houston (US)

How do I manage CARVs in solid organ transplant recipients?

Mike Ison, Chicago (US)
10:30 – 11:50
SSAI Session

Parallel Session 11: The immunodysregulated skin

Alexander Navarini, Basel (CH)

Disseminated Papillomavirus Warts

Vivien Béziat, Paris (FR)

Atopic dermatitis

Patrick M. Brunner, Vienna (AT)

Skin manifestations in autoinflammatory diseases

Sinisa Savic, Leeds (GB)

T cells in the skin: Lymphoma and inflammatory skin disease

Christoph Schlapbach, Berne (CH)
10:30 – 11:50
SSAI Session

Parallel Session 12: Epstein-Barr Virus and associated Diseases

Hiroyuki Yamamoto, Tokyo (JP)

Epstein-Barr Virus - Biology of invasion, stealth and resurrection

Christian Münz, Zurich (CH)

ADA2 deficiency: EBV lymphoproliferation and much more

Isabelle Meyts, Leuven (BE)

EBV diseases in transplantation

Cédric Hirzel, Berne (CH)

Novel inborn errors of immunity underlying susceptibility to EBV infection

Sylvain Latour, Paris (FR)
11:50 – 12:00
General

Time for Room Change

12:00 – 13:20
Industry Symposia

Industry Lunch Symposium - MSD

CMV in the Transplant Patient: What’s New?

Confronting CMV in SOT: Complexities and Complications

CMV in HSCT: Raising the Bar of Clinical Outcomes

What’s Next in Optimizing CMV Prevention: Emerging New Evidence

Interactive Panel Discussion & Q&A

12:00 – 13:20
Industry Symposia

Industry Lunch Symposium - Moderna

Vaccination in the immunocompromised patient

mRNA science in response to a pandemic and potential beyond COVID-19

Melissa Moore

Protection of immunocompromised patients

Giuseppe Pantaleo, Lausanne (CH)

A trial platform for conducting nested trials of mRNA vaccine efficacy for SARS-CoV-2 in immune compromised hosts: The Swiss HIV and Transplant Cohort Studies

Heiner C. Bucher, Basel (CH)

Discussion and Q&A

12:00 – 13:20
General

Lunch Break - Posters / Poster Walk/Industry Expo

13:20 – 13:30
General

Time for Room Change

13:30 – 15:00
ICHS Session

Parallel Session 13: Hepatitis Viruses - Direct and Indirect Challenges

Andri Rauch, Berne (CH) / Roberto Speck, Zurich (CH)

Transplantation with HCV – Milestones on the way to the new normal

Christine Durand, Baltimore (US)

Hepatitis E - Virology and clinical manifestations in the immunocompetent host

Darius Moradpour, Lausanne (CH)

Hepatitis E - Key lessons from Transplantation

Nassim Kamar, Toulouse (FR)

Hepatocellular cancer - mechanisms, personalized profiling and therapy approach

Markus Heim, Basel (CH)
13:30 – 15:00
ICHS Session

Parallel Session 14: Best vaccination for Prevention, Control or Therapy

Lindsey R. Baden, Boston (US) / Maddalena Peghin, Varese (IT)

The Pandemic Challenge: Game-changer for respiratory viruses?

Natasha Halasa, Nashville (US)

The Reactivation challenge: CMV and other herpesviruses in patients at risk

Per Ljungman, Stockholm (SE)

The re-infection challenge: lessons from the malaria vaccine field

Claudia Daubenberger, Allschwil (CH)

The Cure Challenge: Mission impossible or breakthrough for HIV ?

Francesco Simonetti, Baltimore (US)
13:30 – 15:00
SSAI Session

Parallel Session 15: Interferons: The good, the bad, the ugly

Camillo Ribi, Lausanne (CH) / Annette Oxenius, Zurich (CH)

The expanding spectrum of autoinflammatory interferonopathies and their mimics

Raphaela Goldbach-Mansky, Bethesda (US)

What can we learn about type I interferons from murine models

Karl Lang, Essen (DE)

Type I and Type II Interferons in HLH

Jana Pachlopnik, Zurich (CH)

Priming systemic antiviral immunity by the gut microbiota

Nelson Gekara, Stockholm (SE)
13:30 – 15:00
SSAI Session

Parallel Session 16: Tumor immunology

Daniel Speiser, Lausanne (CH) / Martin Bachmann, Berne (CH)

Immunometabolic regulation of T cell function

Christoph Hess, Basel (CH)

Revisiting the role of checkpoint molecule TIM-3 in cancer

Karen Dixon, Boston (US)

Biased Interleukin-2 immunotherapy against poorly-immunogenic and metastatic cancer

Onur Boyman, Zurich (CH)

Shielding Cells for Next Generation Cancer Immunotherapy

Lukas Jeker, Basel (CH)
15:00 – 15:30
General

Time for Room Change

15:15 – 16:45
Industry Symposia

Industry Afternoon Tea Symposium - Novartis Pharma Schweiz AG

Chronic spontaneous urticaria

15:15 – 16:45
Industry Symposia

Industry Afternoon Tea Symposium - Takeda Pharma AG

Secondary Immunodeficiencies

15:15 – 16:45
Industry Symposia

Industry Afternoon Tea Symposium - OM Pharma Suisse SA

15:15 – 16:45
Industry Symposia

Industry Afternoon Tea Symposium - Oxford Immunotec

16:45 – 17:00
General

Time for Room Change

17:00 – 18:30
ICHS Session

Parallel Session 17: Technical or Conceptual Game Changers in Laboratory Diagnostics (Swiss Society for Microbiology)

Gilbert Greub, Lausanne (CH) / Jean Villard, Geneva (CH)

What infectious disease clinicans caring for immunocompromised hosts wants from the lab...

Maddalena Peghin, Varese (IT)

Cell-free DNA and Virus replication: New concepts, challenges, and opportunities

Karoline Leuzinger, Basel (CH)

Comprehensive immune phenotyping - the Immunome: for whom, when and why?

Déla Golshayan, Lausanne (CH)

Metagenomics for Immunocompromised

Adrian Egli, Basel (CH)
17:00 – 18:30
ICHS Session

Parallel Session 18: Infections after Hematopoietic Cell Transplantation (ASTCT and EBMT-sponsored session)

Roy Chemaly, Houston (US) / Rafael de la Camara, Madrid (CH)

Cytokine relases syndrome: CAR-T cells or Sepsis?

Malgorzata Mikulska, Genoa (IT)

Rare Opportunistic Infections after HCT: Nocardiosis and Listeriosis

Dina Averbuch, Jerusalem (IL)

T cell Immunity, T cell Therapy and Viruses: What, when, and how?

Zenia Papanicolaou, New York (US)

COVID-19 in HCT Recipients: specific immune effectors or antivirals?

Sanjeet Dadhwal, City of Hope (US)
17:00 – 18:30
SSAI Session

SSAI General Assembly

19:30 – 23:00
Joint Session

RHINE RIVER CRUISE NETWORKING EVENT

ICHS YOUNG INVESTIGATOR AWARD
ICHS LIFE TIME ACHIEVEMENT AWARD
SSAI AWARD
SYIS AWARD

Preliminary Program SUNDAY

07:00 – 08:00
General

Registration and Room Finding    

08:00 – 08:50
ICHS Session

MEET THE EXPERT 9

The mighty mold – mechanisms, manifestations, management (Case-based)

Mold biology and pathogenesis

Tobias Hohl, New York (US)

Clinical manifestations and management

Thomas Lehrnbecher, Frankfurt (DE)
08:00 – 08:50
ICHS Session

MEET THE EXPERT 10

Do break points: from dilution and diffusion to Maldi-ToF AI

Adrian Egli, Basel (CH)

Do break-proof: optimizing treatment of immunocompromised hosts

Malgorzata Mikulska, Genoa (IT)
08:00 – 08:50
SSAI Session

MEET THE EXPERT 11: Meet the vaccinologist

The difficult to vaccine

Vaccinations in immunodeficiency

Christoph Berger, Basel (CH)

Allergy to vaccines incl. COVID mRNA vaccines

Yannick Mueller, Lausanne (CH)
08:00 – 08:50
SSAI Session

MEET THE EXPERT 12: Meet the ENT specialist

Chronic rhinosinusitis

Primary chronic rhinosinusitis

Simona Nicoleta Negoias, Basel (CH)

ANCA vasculitis, antibody deficiency etc.: Immunologic causes of chronic rhinosinusitis

Thomas Daikeler, Basel (CH)
08:50 – 09:00
General

Time for Room Change

09:00 – 10:00
Joint Session

Plenary Session 5: Epigenetic and Microbiome Immune Regulation

Malgorzata Mikulska, Genoa (IT) / Manuel Battegay, Basel (CH)

The rationale for genetic and epigenetic causes for antibody deficiency

Bodo Grimbacher, Freiburg (DE)

Gut-feeelings: Microbiome and Transplantation

Kate Markey, Seattle (US)
10:00 – 10:30
General

COFFEE BREAK

10:30 – 11:50
ICHS Session

ICHS ABSTRACTS AWARDS

Best Abstracts of Infection & Immunity: What’s new and exciting?

10:30 – 11:50
SSAI Session

SSAI ABSTRACTS AWARDS

Best Abstracts of Infection & Immunity: What’s new and exciting?

11:50 – 12:30
Joint Session

ABSTRACT AWARDS AND CLOSING CEREMONY

11:50 – 12:30
General

FAREWELL & OUTLOOK

Mike Recher, Basel (CH) / Hans H. Hirsch, Basel (CH) / Murat Akova, Ankara (TR)

Color legend:

SSAI SESSIONS
ICHS SESSIONS
JOINT SESSIONS
INDUSTRY SYMPOSIA